The Combined Influences of Exercise, Diet, and Sleep on Neuroplasticity

A 2022 peer-reviewed article published in Frontiers in Psychology explores how three foundational lifestyle behaviors—physical activity, nutrition, and sleep—directly influence neuroplasticity, the brain’s ability to adapt, reorganize, and form new neural connections.

The researchers provide strong evidence that:

  • Exercise, especially aerobic activity, increases levels of BDNF (brain-derived neurotrophic factor), a key protein that supports neuron growth and cognitive function.

  • Dietary patterns rich in omega-3 fatty acids, antioxidants, and polyphenols support brain cell structure and function, while poor diets may impair neuroplasticity.

  • Sleep plays a vital role in memory consolidation, brain detoxification, and maintaining neuroplasticity throughout the lifespan.

The review emphasizes that these lifestyle factors are not just helpful—they are essential for lifelong cognitive resilience and mental health. Together, they shape the physical and functional architecture of the brain.

Why it matters: This growing body of research reinforces the value of a brain-healthy lifestyle—a core principle of our work at the Brain Health and Wellness Lab.

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